Everything is moddable when dealing with software. That means all PC games, as well console games. The issue is "how easy is it to mod"? For example, there are already nude mods out there for DOA5U on xbox (easier to mod than the PS3). If DOA came out on PC, there would undoubtedly be nude mods for it as well.
The question is: "Does that ruin the game?" And my answer is that no, it doesn't. It's not like if Jimmy DLs a nude mod I see his characters as nude whenever he plays me. I'd be more concerned about hackers affecting gameplay, as that would ruin whatever remote ounce of my brain may try to take online seriously.
But I had to say, DOA on PC gives it a chance for a better netcode. So do I think it's worth the risk? Hell yeah. It'll also give it a platform that will carry over into the next console generation without simply re-releasing the game, yet again, for the new consoles.